U.S. Department of Energy

Pacific Northwest National Laboratory

Instrument Development and Deployment

An artist's rendition of the SLIM technology.

Create next-generation technologies to enhance molecular characterization for environmental and biological multi-omics applications

Designing the next generation of therapeutic drugs requires that biophysical samples be analyzed faster than ever, and in better detail. The same is true for samples related to understanding microbial environments at the molecular level.

Analyzing biophysical samples—tissue, blood, soil, and more—is largely the work of ion mobility and mass spectrometry. These analytical technologies require continual improvement in search of better ways to identify a molecule’s shape, mass, functionality, and other characteristics.

Improving related hardware and software is the focus of our Instrument and Development Deployment team.

They are creating the next generation of devices that deliver increased resolution, higher sensitivity, faster turnaround, and smaller sample requirements—all on more portable, robust, and less-expensive platforms. 

Multi-omics applications are central to these next-generation technologies. They flexibly analyze proteins, lipids, and starches in search of metabolic pathways and other signatures of function.


Yehia M. Ibrahim is a senior scientist at the Biological Sciences Division at PNNL. He earned his B.Sc. and M.Sc. degrees in chemistry from Cairo University. His M.Sc. research involved understanding the physicochemical properties of materials using...
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