U.S. Department of Energy

Pacific Northwest National Laboratory

Phenotypic Response of the Soil Microbiome to Environmental Perturbations

Soil samples.

PNNL's Soil Microbiome Science Focus Area (SFA) aims to achieve a systems-level understanding of the soil microbiome's phenotypic response to changing moisture through spatially explicit examination of the molecular and ecological interactions occurring within and between members of microbial consortia. Integrated experiments will be designed to confront both the scaling challenges and inter-kingdom interactions that regulate networks of biochemical reactions. Individual- and population-based microbial community models for predicting interspecies and inter-kingdom interactions will be parameterized using experimental data, and predictions will be tested in soil to reveal spatially explicit microbial interactions. Discoveries and outcomes from controlled experiments will be tested and validated in the field, using moisture gradient experiments at a new local field site. Data will be captured and shared with the broader science community through the establishment of a Soil Microbiome Knowledgebase (SMK). Knowledge gained will provide fundamental understanding of how soil microbial consortia interact to decompose organic carbon and enable prediction of how biochemical reaction networks shift in response to changing moisture regimes.

Team

Aaron Wright leads the Chemical Biology & Exposure Sciences Group in the Biological Sciences Division at PNNL.  His highly collaborative and diverse chemical biology research team is focused on gaining an improved functional and mechanistic...
Janet Jansson is Chief Scientist for Biology in the Biological Sciences Division and a laboratory fellow at the Pacific Northwest National Laboratory (PNNL). Currently Dr. Jansson is the lead for the Microbiome in Transition initiative and the...
Dr. Jason McDermott, senior research scientist, has extensive research experience in molecular and structural virology and data resource design, data integration and prediction of biological networks, bridging experimental and computational biology...
I received my PhD in Chemistry in the Department of Chemistry and Biochemistry at the University of South Carolina with Dr. John W. Baynes, who studied the role of the Maillard reaction in the development of diabetic complications and in aging. ...
Hyun Song’s research is directed toward developing modeling and computational tools for the simulation of cellular metabolism and microbial community dynamics. His research interest in metabolic modeling includes 1) omics data-guided estimation of...
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